Hydrogel Pressure Sealant System

摘要

The present invention includes devices, systems, and methods for sealing a defect in body tissue. For example, the present invention includes a device for preventing leakage of air and other gases from the lung during and after lung biopsy. The device delivers a hydrogel composition which forms an air-tight sealant. In certain embodiments, the device simultaneously delivers one or more therapeutic agents, such as lidocaine, to the treatment area.

主权项

1. A device for sealing a tissue defect in a body tissue of a subject, wherein the device comprises:
a first barrel and a first plunger engaged with the proximal end of the first barrel, thereby forming a first chamber within the first barrel, wherein the first chamber houses a first component of a hydrogel; a second barrel and a second plunger engaged with the proximal end of the second barrel, thereby forming a second chamber within the second barrel chamber, and wherein the second chamber houses a second component of a hydrogel; and at least one port connecting the first chamber and second chamber; wherein the contents of the first chamber and second chamber are temporarily isolated to prevent contact of the first component and second component prior to mixing.