发明名称 |
BILE ACID-BASIC AMINO ACID CONJUGATES AND USES THEREOF |
摘要 |
Compositions and methods for treating diseases or disorders associated with the metabolic syndrome using conjugates of bile acids with basic amino acids or a decarboxylated amino acid such as agmatine are provided. Further provided are bile acid-basic amino acid conjugates including chenodeoxycholic acid with an amino acid selected from arginine, lysine, histidine, ornithine or a decarboxylated amino acid such as agmatine. |
申请公布号 |
US2016120880(A1) |
申请公布日期 |
2016.05.05 |
申请号 |
US201414895723 |
申请日期 |
2014.06.05 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. |
发明人 |
TIROSH Oren;VOLOSHIN Ira;SASSON Shlomo;OBERCYGER Michal;MADAR Zecharia |
分类号 |
A61K31/575;A61K47/48;C07J41/00 |
主分类号 |
A61K31/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Jerusalem IL |