| 主权项 |
1. A valve prosthesis device suitable for cardiac implantation in corporeal ducts, the device comprising:
a support stent comprising a proximal portion and a distal portion, wherein the support stent comprises an annular frame adapted to be crimped in a first narrow configuration and be radially deployable so as to extend to a second expanded configuration to occupy a passage at the target location for implantation in the corporeal duct, and a valve assembly comprising a flexible conduit formed from pliant material formed into leaflets and having an inlet and an outlet, wherein the flexible conduit provides collapsible slack portions arranged to open to permit fluid flow from the inlet to the outlet and to collapse to prevent fluid flow from the outlet to the inlet, wherein when flow is allowed to pass through the valve prosthesis device from the inlet to the outlet, the valve assembly is kept in an open position; wherein a reverse flow is prevented as the collapsible slack portions of the valve assembly collapse inwardly providing blockage to the reverse flow; and wherein, in the second expanded configuration, the device is configured so that retrograde flow will be altered from laminar flow and directed towards the leaflets to effect closing. |
