发明名称 INHIBITOR FOR RETINOCHOROIDAL DISORDERS
摘要 The present invention addresses the problem of providing an inhibitor for retinochoroidal disorders, in particular, an inhibitor for retinochoroidal scar formation and retinochoroidal atrophy in an epiretinal, intraretinal or subretinal tissue. This problem can be solved by preparing an inhibitor for retinochoroidal disorders which comprises, as an active ingredient, (E)-4-(2-{3-[(1H-pyrazol-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof or a salt of the same. The inhibitor for retinochoroidal disorders can inhibit collagen atrophy of retinal pigment epithelium cells, fibroblasts, glial cells and the like and thus inhibit retinochoroidal disorders.
申请公布号 US2016120843(A1) 申请公布日期 2016.05.05
申请号 US201414892536 申请日期 2014.05.21
申请人 YAMAGUCHI UNIVERSITY 发明人 KIMURA Kazuhiro
分类号 A61K31/415 主分类号 A61K31/415
代理机构 代理人
主权项 1. An inhibitor for a retinochoroidal disorder comprising (E)-4-(2-{3-[(1H-pyrazole-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof, or a salt thereof as an effective ingredient.
地址 Yamaguchi-shi, Yamaguchi JP