发明名称 |
Composition of a non-nucleoside reverse transcriptase inhibitor |
摘要 |
The invention encompasses a composition comprising the reverse transcriptase ("RT") inhibitor 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile sufficiently mixed in a concentration enhancing polymer, and processes for making the same. The composition and processes of the present invention significantly improve the bioavailability of the aforementioned RT inhibitor, while maintaining physical stability. |
申请公布号 |
AU2014353177(A1) |
申请公布日期 |
2016.05.05 |
申请号 |
AU20140353177 |
申请日期 |
2014.11.19 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
LOWINGER, MICHAEL;TATAVARTI, ADITYA S.;MARSAC, PATRICK JULES;PLOEGER, KRISTIN J. M.;BLOOM, COREY J.;BROOKHART, KATHERINE ANNE |
分类号 |
A01N43/40 |
主分类号 |
A01N43/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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