| 发明名称 |
Pharmaceutical Composition Suitable for Treatment of Haemophilia |
| 摘要 |
The present invention relates to pharmaceutical compositions suitable for treatment of haemophilia. |
| 申请公布号 |
US2016120954(A1) |
申请公布日期 |
2016.05.05 |
| 申请号 |
US201514934196 |
申请日期 |
2015.11.06 |
| 申请人 |
NOVO NORDISK A/S |
发明人 |
Bolt Gert;Karpf Ditte M.;Rode Frederik;Haaning Jesper;Roepstorff Kirstine;Thim Lars;Petersen Maj;Kjalke Marianne;Olsen Ole Hvilsted;Noerby Peder L.;Hansen Jens J. |
| 分类号 |
A61K38/37;A61K38/36;C07K14/755 |
主分类号 |
A61K38/37 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Use of a pharmaceutical composition comprising a FVIII molecule for treatment of haemophilia, wherein said FVIII molecule comprises a truncated B domain at a size of 100-400 amino acids, wherein the amino acid sequence of said truncated B domain is derived from the wt FVIII B domain amino acid sequence, and wherein the bioavailability of said FVIII molecule is at least 10% in connection with s.c. administration. |
| 地址 |
Bagsvaerd DK |
