发明名称 COMPOSITIONS AND METHODS COMPRISING BACTERIA FOR IMPROVING BEHAVIOR IN NEURODEVELOPMENTAL DISORDERS
摘要 Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in need thereof. The subject in need thereof can have a gut microbiota signature characteristic of an adult. The bacterial species can include Bacteroides (e.g., B. fragilis, B. thetaiomtaomicron, and/or B. vulgatus), and/or Enterococcus (e.g., E. faecalis, E. faecium, E. hirae, E. avium, E. durans, E. gallinarum, or E. casseliflavus). Upon treatment, one or more ASD-related behaviors can be improved in the subject.
申请公布号 US2016120917(A1) 申请公布日期 2016.05.05
申请号 US201514925510 申请日期 2015.10.28
申请人 California Institute of Technology 发明人 Bailey Antoinette;Mazmanian Sarkis K.;Patterson Paul H.
分类号 A61K35/741;A61K35/744 主分类号 A61K35/741
代理机构 代理人
主权项 1. A method for improving behavioral performance in a human, the method comprising: identifying a human subject having a gut microbiota signature comprising at least 500 different species of microbes; and administering to the human subject an effective amount of one or more Bacteroides bacteria.
地址 Pasadena CA US