METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR VISUALIZATION OF RESECTION TARGET DURING EPILEPSY SURGERY AND FOR REAL TIME SPATIOTEMPORAL VISUALIZATION OF NEUROPHYSIOLOGIC BIOMARKERS

摘要

The subject matter described herein relates to methods, systems, and computer readable media for visualization of a resection target during epilepsy surgery and for real time spatiotemporal visualization of neurophysiologic biomarkers. One exemplary method includes a real time neurophysiologic biomarker visualization system implemented by at least one computer, receiving, as input, a pre-electrode-implantation MRI of an epilepsy patient's brain.

主权项

1. A method for visualization of a resection target during epilepsy surgery, the method comprising:at a real time neurophysiologic biomarker visualization system implemented by at least one computer:
receiving, as input, a pre-electrode-implantation magnetic resonance image (MRI) of an epilepsy patient's brain; receiving, as input, a post-electrode-implantation computed tomography (CT) image of the patient's brain; receiving, as input, a post-electrode-implantation MRI of the patient's brain; receiving, as input, raw EEG data produced by an implanted electrode array, processing the raw EEG data, and generating a visualization of occurrences of a neurophysiologic biomarker mapped to locations of the occurrences of the neurophysiologic biomarker; receiving, as input, data identifying a resection target; and receiving, as input, relative coordinates in real space produced by a neuronavigation system; registering the MRIs, the CT image, the visualization of the occurrences of the neurophysiologic biomarker, the data identifying the resecting target and the relative coordinates in real space produced by the neuronavigation system and outputting the registered image.