发明名称 |
SHIP1 MODULATORS AND METHODS RELATED THERETO. |
摘要 |
Compounds of formula (II): wherein A, R1, R2, R5 and R13 are described herein, or a stereoisomer, enantiomer or tautomer thereof or mixtures thereof, or a pharmaceutically acceptable salt or solvate thereof, are described herein, as well as other compounds. These compounds have activity as SHIP1 modulators, and thus may be useful in treating a variety of diseases, disorders or conditions that would benefit from SHIP1 modulation. Compositions comprising a compound of the invention are also disclosed, as are methods of SHIP1 modulation by administration of such compounds to an animal in need thereof. |
申请公布号 |
MX2015012111(A) |
申请公布日期 |
2016.05.05 |
申请号 |
MX20150012111 |
申请日期 |
2014.02.27 |
申请人 |
AQUINOX PHARMACEUTICALS (CANADA) INC. |
发明人 |
BOGUCKI, DAVID;RAYMOND, JEFFERY R.;MACKENZIE, LLOYD F.;MACRURY, THOMAS B.;PETTIGREW, JEREMY D.;HARWIG, CURTIS |
分类号 |
C07D213/75;A61K31/047;A61P29/00;C07C35/21;C07C35/32;C07C215/26;C07C215/38;C07C233/23;C07C275/22;C07C335/10;C07D213/82;C07D215/227;C07D221/18;C07D231/54;C07D333/20 |
主分类号 |
C07D213/75 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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