发明名称 |
SPECIFIC CANCER TREATMENT REGIMES WITH GANETESPIB |
摘要 |
Methods of treating certain types of cancer with ganetespib are disclosed. Also provided are methods of treating certain types of cancer with ganetespib in combination with a taxane derivative, and a platinum-containing anticancer agent. Also provided are methods of treating certain types of cancer with p53 mutation by a combination of ganetespib with a taxane derivative, and a platinum-containing anticancer agent. Also provided are methods of treating certain types of cancer with ganetespib in combination with a platinum-containing anticancer agent, and an antimetabolite. Also provided are methods of treating certain types of cancer with ganetespib in combination with a taxane derivative, an anthracycline derivative, and an alkylating antineoplastic agent. Also provided is a pharmaceutical composition comprising ganetespib and one or more other anticancer agents as described above. |
申请公布号 |
US2016120848(A1) |
申请公布日期 |
2016.05.05 |
申请号 |
US201414892761 |
申请日期 |
2014.05.20 |
申请人 |
SYNTA PHARMACEUTICALS CORP. |
发明人 |
Vukovic Vojo |
分类号 |
A61K31/4196;A61K33/24;A61K31/704;A61K31/519;A61K31/675;A61K31/337;A61K31/282 |
主分类号 |
A61K31/4196 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating cancer in a subject, comprising administering an effective amount of ganetespib or a pharmaceutically acceptable salt thereof, in combination with a taxane derivative and a platinum-containing anti-cancer agent. |
地址 |
Lexington MA US |