Método para la valoración de riesgo cardiovascular no clásico mediante la detección de autoanticuerpos anti-lipoproteínas de alta densidad, inmunosensor y kit para su aplicación

摘要

The invention relates to a method for assessing non-classical cardiovascular risk by means of detection of anti-high-density-lipoprotein autoantibodies, to an immunosensor, and to a kit for the application thereof. The method comprises bringing a sample of the subject into contact with human HDL particles in conditions such that a detectable specific antigen-antibody union may occur, and stratifying the cardiovascular risk of the subject by comparing the result obtained in the analysis of the sample with those obtained in the healthy population. The invention is applicable in the sectors of biotechnology and pharmacology and in that of medicine and clinical diagnostics, and more specifically in the assessment of cardiovascular risk to prevent diseases using biomarkers in different groups of patients.