SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS

摘要

Disclosed herein are polymers made from at least one monomer of formulae (I), (II), (III), and (IV), in combination with a monomer of formula (V) that may be used in pharmaceutical formulations. These polymers comprise a hydrocarbon backbone and are made from monomers that contain at least one carbon-carbon double bond. Methods of making these polymers are also disclosed.

主权项

1. A polymer having an acrylate-derived backbone, where the polymer comprises at least two monomeric units, wherein the first monomeric unit is derived from the monomers selected from the group consisting of:and the second monomeric unit is derived from monomer of formula:whereinat each occurrence, R1, R2 and R3 are independently H or methyl;R4 is H or C1-C6 alkyl;R6 is C1-C6 alkyl; andat each occurrence, R10 is independently H, C1-C4 alkyl, C2-C4 alkanoyl, C2-C5 alkenoyl, —C1-C4 alkyl-aryl, or -alkanoylaryl;wherein the C2-C6 hydroxyalkyl group has one or two OH groups.