发明名称 |
Method |
摘要 |
In one aspect the present invention provides a method for selecting a cell or cell colony which produces a polypeptide of interest, comprising a) providing a medium comprising cells and a detection agent, wherein the detection agent is associated with a detectable signal and the detection agent is capable of binding to the polypeptide of interest; b) providing a solid phase having a capture agent disposed thereon, wherein the capture agent is capable of binding to the polypeptide of interest; c) contacting the medium with the solid phase; d) detecting the signal associated with the detection agent; and e) selecting a cell or cell colony associated with the signal, wherein presence of the signal is indicative of a cell or cell colony which produces the polypeptide of interest. |
申请公布号 |
EP2437057(B1) |
申请公布日期 |
2016.05.04 |
申请号 |
EP20110183497 |
申请日期 |
2011.09.30 |
申请人 |
MOLECULAR DEVICES (NEW MILTON) LTD |
发明人 |
BURKE, JULIAN;ROBERTSON, ALASDAIR;ZHANG, XIAO |
分类号 |
G01N33/50;G01N33/543;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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