发明名称 |
METHOD OF PRODUCING OPTICALLY ACTIVE N-(HALOPROPYL)AMINO ACID DERIVATIVE |
摘要 |
The present invention provides a method for producing an optically active N-(halopropyl)amino acid derivative, wherein the method comprises the steps of obtaining a compound represented by formula (III) by reacting an optically active alanine ester represented by formula (I) or a salt thereof (hereinafter sometimes simply referred to as an "alanine ester") with a halogenated propane represented by formula (II); and obtaining an optically active N-(halopropyl)amino acid derivative represented by formula (IV) by introducing a protecting group onto the nitrogen atom of the compound represented by formula (III). The present invention provides a method for efficiently producing an optically active N-(halopropyl)amino acid derivative. |
申请公布号 |
EP2192110(B1) |
申请公布日期 |
2016.05.04 |
申请号 |
EP20080753110 |
申请日期 |
2008.05.19 |
申请人 |
NAGASE & CO., LTD. |
发明人 |
MATSUMOTO, JUN;INOUE, TORU |
分类号 |
C07C231/02;C07B53/00;C07C227/14;C07C227/30;C07C229/12;C07C233/83;C07C269/04;C07C271/22 |
主分类号 |
C07C231/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|