| 摘要 |
An implantable device (11) for evaluating autonomic cardiovascular drive, comprising:
an implantable neurostimulator (12) comprising a pulse generator configured to deliver electrical therapeutic stimulation tuned to restore autonomic balance through continuously-cycling, intermittent and periodic electrical pulses delivered in a manner that results in creation and propagation (in both afferent and efferent directions) of action potentials within neuronal fibers comprising a cervical vagus nerve (15, 16, 61) of a patient (10) in continuous alternating cycles of stimuli application and stimuli inhibition (90) and configured to deliver the electrical therapeutic stimulation according to stored stimulation parameters comprising the pulse width falling within the range of 100 to 250 µsec, the output current (96) falling within the range of 0.02 to 50 mA, and the signal frequency (93) at least being 10 Hz;
a cervical vagus nerve stimulation therapy lead (13) electrically coupled to the pulse generator and terminated by a at least one electrode through which the therapeutic electrical stimulation is delivered to the patient's cervical vagus nerve (15, 16, 61). |
