发明名称 |
MICROSPHERES OF HYDROLYSED STARCH WITH ENDOGENOUS, CHARGED LIGANDS |
摘要 |
Biodegradable microspheres having a diameter of 10-2000 μm having cross-linked hydrolysed starch onto which at least one type of ligand has been coupled via a carboxylic ester bond. The ligand shall be an endogenous, charged molecule with a molecular mass of less than 1000 Da having at least one additional carboxylic acid function in addition to the one utilised for coupling the ligand to the microsphere and/or at least one amine function. On average 0.05-1.5 ligands are coupled to each glucose moiety in the hydrolysed starch. |
申请公布号 |
EP2506859(B1) |
申请公布日期 |
2016.05.04 |
申请号 |
EP20100834831 |
申请日期 |
2010.11.17 |
申请人 |
MAGLE AB |
发明人 |
MALMSJÖ, MALIN;THORDARSON, EDDIE;APELL, STEN PETER;FYHR, PETER |
分类号 |
A61K31/718;A61K9/14;A61K9/16;A61L15/28;A61L15/64;A61L24/08;C08B31/00;C08B31/04;C08J9/00;C12N5/00 |
主分类号 |
A61K31/718 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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