发明名称 |
Nuevos péptidos y procedimientos para su preparación y uso |
摘要 |
The present invention is in the field of treatment of diabetes and relates to peptides that exhibit activity for both glucose-dependent insulinotropic peptide receptor (GIP-R) and glucagon-like peptide-1 receptor (GLP-1-R) and are selective over glucagon receptor (Gluc-R). Specifically provided are GIP analogs with amino acid substitutions introduced to modulate activity for both GIP-R and GLP-1-R and maintain selectivity over Gluc-R. |
申请公布号 |
ES2568796(T3) |
申请公布日期 |
2016.05.04 |
申请号 |
ES20110711424T |
申请日期 |
2011.03.23 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
ALSINA-FERNANDEZ, Jorge;BOKVIST, Krister Bengt;GUO, Lili;MAYER, John Philip |
分类号 |
A61K38/16;A61K38/26;A61K38/30;C07K14/47;C07K14/605;C07K14/62 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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