Contact lenses having sensors with adjustable sensitivity

摘要

Apparatus and methods employing contact lenses having electrochemical sensors that have adjustable analyte-sensing sensitivity are provided. In some aspects, level of the analyte or biological substance is detected and a number of sub-electrodes of the sensor are turned on or off based on the level of the analyte or biological substance. The sensitivity of the sensor is adjusted based on the number of sub-electrodes that are turned on or off. In some aspects, the current level from the sensor is employed in determining the number of sub-electrodes to turn on or off. In one aspect, a contact lens includes: a substrate; a power component; a circuit and an adjustment circuit. The circuit can include a potentiostat; and a sensor electrically coupled to the potentiostat, and configured to sense a level of an analyte. The sensitivity of the sensor can be adjustable by the adjustment circuit.

主权项

1. A contact lens, comprising:
a substrate; a power component, disposed on or within the substrate, configured to output power; a potentiostat, disposed on or within the substrate, and configured to be powered by the power component; a sensor, disposed on or within the substrate, electrically coupled to the potentiostat, and configured to sense a level of an analyte in an eye over which the contact lens is configured to be worn, wherein the sensor comprises a working electrode having a plurality of sub-electrodes, and wherein a sensitivity of the sensor is adjustable; and an adjustment circuit, disposed on or within the substrate, electrically coupled to the sensor, and configured to control the sensitivity of the sensor by turning one or more of the plurality of sub-electrodes on or off to the potentiostat.