| 摘要 |
According to the present invention, novel means for more reliably detecting sensitivity to INH in Mycobacterium tuberculosis, that is, detecting whether or not M . tuberculosis is an INH-resistant bacterium is provided. A method for detecting sensitivity to Isoniazid in M . tuberculosis, comprising the steps of obtaining a fabG1 gene of M . tuberculosis in a sample; and detecting a mutation involved in resistance to Isoniazid with respect to the obtained fabG1 gene. The method of the invention may, if necessary, comprise a step of detecting a mutation in a furA gene of M . tuberculosis, and may preferably be combined with another known method for detecting sensitivity to Isoniazid. |
