发明名称 Composition for treating, improving, or preventing pain
摘要 In order to provide a composition for treating, improving, or preventing pain, it has been found out that a metallothionein protein is expressed in a normal peripheral nerve, and that the expression is not observed in a peripheral nerve producing pain. Moreover, it has been found out that administering metallothionein to rats having neuropathic pain suppresses the pain in the rats.
申请公布号 US9327012(B2) 申请公布日期 2016.05.03
申请号 US201214001212 申请日期 2012.02.23
申请人 SAPPORO MEDICAL UNIVERSITY 发明人 Kokai Yasuo;Ooki Gousuke;Matsumoto Kayo;Imai Shinichi;Wada Takuro
分类号 A61K38/17;C07K14/825;A61K31/713;G01N33/68;A61K38/00;A61K48/00 主分类号 A61K38/17
代理机构 Sughrue Mion, PLLC 代理人 Sughrue Mion, PLLC
主权项 1. A method for treating, improving, or preventing pain, the method comprising administering any one of a full length metallothionein protein, a gene encoding the protein, and a vector in which the gene is inserted; excluding a method for treating, improving, and preventing, wherein the pain is due to heavy-metal poisoning.
地址 Sapporo-shi, Hokkaido JP