发明名称 |
Composition for treating, improving, or preventing pain |
摘要 |
In order to provide a composition for treating, improving, or preventing pain, it has been found out that a metallothionein protein is expressed in a normal peripheral nerve, and that the expression is not observed in a peripheral nerve producing pain. Moreover, it has been found out that administering metallothionein to rats having neuropathic pain suppresses the pain in the rats. |
申请公布号 |
US9327012(B2) |
申请公布日期 |
2016.05.03 |
申请号 |
US201214001212 |
申请日期 |
2012.02.23 |
申请人 |
SAPPORO MEDICAL UNIVERSITY |
发明人 |
Kokai Yasuo;Ooki Gousuke;Matsumoto Kayo;Imai Shinichi;Wada Takuro |
分类号 |
A61K38/17;C07K14/825;A61K31/713;G01N33/68;A61K38/00;A61K48/00 |
主分类号 |
A61K38/17 |
代理机构 |
Sughrue Mion, PLLC |
代理人 |
Sughrue Mion, PLLC |
主权项 |
1. A method for treating, improving, or preventing pain, the method comprising administering any one of a full length metallothionein protein, a gene encoding the protein, and a vector in which the gene is inserted; excluding a method for treating, improving, and preventing, wherein the pain is due to heavy-metal poisoning. |
地址 |
Sapporo-shi, Hokkaido JP |