发明名称 Method of treating organism by biologically active compounds specifically delivered into mitochondria, pharmaceutical composition required for the use of the method and a compound applicable for this purpose
摘要 This invention relates to biology and medicine and, in particular, can be used in medicine to make a pharmaceutical composition for targeted delivery of biologically active substances into mitochondria, driven by proton electro-chemical potential in the mitochondria. This invention also relates to the method to affect an organism by the targeted delivery of biologically active compounds to mitochondria. The invention can be useful in treatment of diseases or disorders associated with not normal functioning of mitochondria, in particular diseases associated with increased production of free radicals and reactive oxygen species.
申请公布号 US9328130(B2) 申请公布日期 2016.05.03
申请号 US200811972437 申请日期 2008.01.10
申请人 MITOTECH S.A. 发明人 Skulachev Vladimir Petrovich
分类号 A01N57/00;A61K31/66;C07D311/82;C07F9/54;A61K47/48 主分类号 A01N57/00
代理机构 Verrill Dana LLP 代理人 Keown Wayne A.;Verrill Dana LLP
主权项 1. A compound having antioxidant activity, which is selected from the group consisting of:
地址 Luxembourg LU