发明名称 Substituted xanthine derivatives
摘要 This invention relates to novel compounds that are substituted xanthine derivatives and pharmaceutically acceptable salts thereof. For example, this invention relates to novel substituted xanthine derivatives that are derivatives of pentifylline. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions for which pentifylline and related compounds are beneficial.
申请公布号 US9328113(B2) 申请公布日期 2016.05.03
申请号 US201314391443 申请日期 2013.04.12
申请人 Concert Pharmaceuticals, Inc. 发明人 Tung Roger D.;Pandya Bhaumik;Harbeson Scott L.
分类号 C07D473/10;C07D487/04 主分类号 C07D473/10
代理机构 McCarter & English, LLP 代理人 McCarter & English, LLP ;Davis Steven G.;Dertz Emily
主权项 1. A compound of Formula A: or pharmaceutically acceptable salts thereof, wherein each of X1a, X1b, X2a, and X2b is deuterium; each of X3a, X3b, X4a, X4b, X5a, X5b and X6 is hydrogen; R1 is —CD3; and each of R2 and R3 is independently CH3 or CD3.
地址 Lexington MA US