| 发明名称 | <i>Campylobacter </i>immunogenic compositions and uses thereof | ||
| 摘要 | The present invention provides immunogenic compositions against Campylobacter and methods for using the immunogenic composition to generate an immune response against Campylobacter and/or reduce intestinal colonization by Campylobacter. | ||
| 申请公布号 | US9328148(B2) | 申请公布日期 | 2016.05.03 |
| 申请号 | US201314375365 | 申请日期 | 2013.02.01 |
| 申请人 | The Arizona Board of Regents on Behalf of the University of Arizona | 发明人 | Joens Lynn A.;Law Bibiana;Armstrong Alexandra |
| 分类号 | C07H21/02;C12N15/00;C07K14/205;A61K39/02;C12N15/74;A61K39/00 | 主分类号 | C07H21/02 |
| 代理机构 | McDonnell Boehnen Hulbert & Berghoff LLP | 代理人 | McDonnell Boehnen Hulbert & Berghoff LLP |
| 主权项 | 1. An immunogenic composition, comprising one or more expression vectors comprising: (a) one or more polynucleotide encoding two or more proteins including (i) a protein comprising an amino acid sequence at least 80 percent identical to SEQ ID NO:2 (Cj0998c protein), or antigenic portions thereof, and(ii) at least one protein comprising an amino acid sequence at least 80 percent identical to SEQ ID NO:4 (Cj0588 protein), and/or SEQ ID NO:6 (Cj0248 protein), or antigenic portions thereof; and (b) a promoter operatively linked to the one or more polynucleotide, wherein the promoter region is capable of directing expression of the encoded protein(s). | ||
| 地址 | Tucson AZ US | ||