Tubular patent foramen ovale (PFO) closure device with catch system

摘要

Occluder devices for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO) comprise two sides connected by a central tube. The occluder devices are formed from a tube, which is cut to produce struts in each side. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. In some embodiments, at least one of the sides includes a tissue scaffold. The occluder devices include a catch system that maintains its deployed state in vivo. When an occluder device is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system is deployed so that the occluder device exerts a compressive force on the septal tissue and closes the aperture.

主权项

1. An occluder device for occluding a defect in a body, the occluder device having a delivery configuration in which the occluder device is adapted to be delivered through the body's vasculature and a deployed configuration in which the occluder device is adapted to occlude the defect, the occluder device comprising:
a central tube portion; a proximal side comprising a proximal end tube portion and a plurality of proximal struts, the plurality of proximal struts comprising (i) a first proximal strut portion directly extending from the central tube portion, (ii) a second proximal strut portion directly extending from the proximal end tube portion, and (iii) a proximal circumferential strut portion extending between the first proximal strut portion and the second proximal strut portion, the proximal end tube portion forming a first terminal end of the occluder device, wherein the proximal circumferential strut portion is thinner than the first proximal strut portion, and wherein the proximal circumferential strut portion is thinner than the second proximal strut portion; and a distal side comprising a distal end tube portion and a plurality of distal struts, the plurality of distal struts comprising (i) a first distal strut portion directly extending from the central tube portion, (ii) a second distal strut portion directly extending from the distal end tube portion, and (iii) a distal circumferential strut portion extending between the first distal strut portion and the second distal strut portion, the distal end tube portion forming a second terminal end of the occluder device, wherein the distal circumferential strut portion is thinner than the first distal strut portion, and wherein the distal circumferential strut portion is thinner than the second distal strut portion, wherein, in the deployed configuration, the plurality of proximal struts form a plurality of proximal loops that all lie generally entirely within a proximal side plane and the plurality of distal struts form a plurality of distal loops that all lie generally entirely within a distal side plane, and wherein the central tube portion is positioned at an angle with respect to the proximal and distal side planes.