| 发明名称 | Nitrogen-containing biphenyl compounds, pharmaceutical compositions of same, preparation methods and anti-HIV-1 uses thereof | ||
| 摘要 | Nitrogen-containing biphenyl compounds as represented by formula (I), pharmaceutically acceptable salts or derivatives thereof, pharmaceutical compositions, and preparation methods therefore, and anti-HIV-1 use of the compound. Each substituent group in formula (I) is as defined in the description.; | ||
| 申请公布号 | US9328084(B2) | 申请公布日期 | 2016.05.03 |
| 申请号 | US201113880487 | 申请日期 | 2011.10.13 |
| 申请人 | Kunming Institute of Botany, The Chinese Academy of Sciences;Yunnan University;Kunming Institute of Zoology, The Chinese Academy of Sciences | 发明人 | Liu Jingping;Sun Handong;Zhang Hongbin;Zheng Yongtang;Xiao Weilie;Pu Jianxin;Wang Ruirui;Yang Liumeng |
| 分类号 | C07D317/68;A61K31/5377 | 主分类号 | C07D317/68 |
| 代理机构 | Honigman Miller Schwartz and Cohn LLP | 代理人 | Honigman Miller Schwartz and Cohn LLP ;Wootton, Esq. Thomas A.;O'Brien Jonathan P. |
| 主权项 | 1. The nitrogen-containing biphenyl compound having the following structural formula (I) or (II): wherein R1 is selected from the group consisting of OH, OCH2Ph and OR; R2 and R3 together form —OCH2O—; R4 is selected from the group consisting of H, OH, OCH2Ph, OR, and I; R5 is selected from the group consisting of OCH2Ph and OR; R6 and R7 are selected from the group consisting of aliphatic hydrocarbyl containing 1-10 carbon atoms; R8 is selected from the group consisting of H, CH2Ph and aliphatic hydrocarbyl; R9 is selected from the group consisting of H and aliphatic hydrocarbyl; R is selected from the group consisting of aliphatic hydrocarbyl and aryl; X is Cl. | ||
| 地址 | Kunming CN | ||