| 主权项 |
1. A method of monitoring renal nerve activity, the method comprising:
deploying a nerve monitoring assembly in a renal artery of a human patient, wherein the nerve monitoring assembly comprises a first electrode array at a distal portion of a shaft and a second electrode array spaced laterally apart from the first electrode array, wherein deploying the nerve monitoring assembly in the renal artery further comprises inflating a first balloon within the renal artery, wherein the inflated first balloon contacts an inner wall of the renal artery, and wherein the first and second electrode arrays are on an outer surface of the first balloon; delivering a neuromodulation assembly to a target site within the renal artery between the first and second electrode arrays, wherein delivering the neuromodulation assembly to the target site within the renal artery between the first and second electrode arrays further comprises inflating a second balloon within the first balloon, wherein the second balloon is configured to contact the first balloon to define a neuromodulation region; stimulating renal nerves with the first electrode array, wherein the stimulation energy is at a magnitude which induces renal nerve activity; recording, with the second electrode array, renal nerve activity resulting from the stimulating act; and applying therapeutically-effective neuromodulation energy to the target site with the neuromodulation assembly, wherein the neuromodulation energy is at a level which inhibits, reduces, or blocks renal nerves, and wherein applying therapeutically-effective neuromodulation energy to the target site with the neuromodulation assembly further comprises applying cryogenic cooling to the renal artery proximate the neuromodulation region. |
