| 发明名称 | Oleyl phosphocholine | ||
| 摘要 | The invention relates to the use of oleyl phosphocholine and oleyl-phospho-(N.N.-dimethyl-N-ethyl)-ethyl-ammonium for the long-term and continuous treatment of serious illnesses, such as cancer, leishmaniasis, ehrlichiosis, multiple sclerosis and psoriasis, in addition to other indications mentioned in the application. | ||
| 申请公布号 | US9326989(B2) | 申请公布日期 | 2016.05.03 |
| 申请号 | US200812593336 | 申请日期 | 2008.03.26 |
| 申请人 | Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V. | 发明人 | Eibl Hansjörg |
| 分类号 | A61K31/685;A61K45/06 | 主分类号 | A61K31/685 |
| 代理机构 | Rothwell, Figg, Ernst & Manbeck, P.C. | 代理人 | Rothwell, Figg, Ernst & Manbeck, P.C. |
| 主权项 | 1. A method for the treatment of protozoan diseases, bacterial diseases, cancer, multiple sclerosis, acariosis, eye diseases, fungal diseases and/or psoriasis, in a patient in need of such treatment while avoiding the concomitant liability of toxicity associated with said treatment when administering an effective dose of hexadecyl phosphocholine, comprising administering to the patient a compound of the formula (I) R1—O—PO2(−)—O—(CH2)2—N(+)—R2(CH3)2 (I) wherein R1 is an oleyl residue and R2 is CH3, in an amount of 0.1 to 0.9 mg/kg body weight/day. | ||
| 地址 | Munich DE | ||