发明名称 |
STABLE POLYPEPTIDES BINDING TO HUMAN COMPLEMENT C5 |
摘要 |
The invention relates to a polypeptide capable of binding human complement component 5 (C5), said polypeptide comprising the amino acid sequence [BM]-[L2]-QSX42X43LLX46EAKKLX52X53X54Q wherein [BM] is a C5 bindingmotif; [L2] is an interconnecting loop; X42 is selected from A and S; X43 is selected from N and E; X46 is selected from A, S and C; X52 is selected from E, N and S; X53 is selected from D, E and S, provided that X53 is not D when X52 is N; and X54 is selected from A and S. |
申请公布号 |
PH12016500371(A1) |
申请公布日期 |
2016.05.02 |
申请号 |
PH12016500371 |
申请日期 |
2016.02.24 |
申请人 |
SWEDISH ORPHAN BIOVITRUM AB (PUBL) |
发明人 |
NILSSON, JOAKIM;NORDLING, ERIK;STROMBERG, PATRIK |
分类号 |
A61K38/00;C07K14/47 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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