发明名称 |
COMPLEX CHROMOSOME ENGINEERING FOR PRODUCTION OF HUMAN ANTIBODIES IN TRANSGENIC ANIMALS |
摘要 |
The invention relates to large-scale production of human antibodies by transgenic animals with high production of fully human IgG up to >10 g/L in sera with human IgG1 subclass dominancy. This invention also supports a feasibility of complex chromosome engineering for complicated genetic studies in non-murine mammalian species. |
申请公布号 |
HK1210621(A1) |
申请公布日期 |
2016.04.29 |
申请号 |
HK20150111388 |
申请日期 |
2015.11.18 |
申请人 |
SAB LLC |
发明人 |
KUROIWA, YOSHIMI;MATSUSHITA, HIROAKI;SANO, AKIKO |
分类号 |
C07K;A01K;C12N |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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