发明名称 Stable formulations of a hyaluronan-degrading enzyme
摘要 Discloses a stable co-formulation composition, wherein: the composition has a pH of between or between about 6.8 and 7.8; and the composition comprises: a) an insulin or insulin analogue; b) a hyaluronidase; c) NaCl; d) a stabilising agent or agents; and e) one or more preservative agents comprising a phenolic preservative, whereby the composition is stable for at least 6 months at a temperature from or from about 2°C to 8°C, inclusive, and/or for at least 14 days at a temperature from or from about 20°C to 30°C, inclusive.
申请公布号 NZ618331(A) 申请公布日期 2016.04.29
申请号 NZ20120618331 申请日期 2012.06.15
申请人 HALOZYME INC. 发明人 VAUGHN DANIEL EDWARD;YANG TZUNG-HORNG;LABARRE MICHAEL JAMES;CASTER CHRISTOPHER L.;NICOL FRANCOIS;KIM DONGHYUN
分类号 A61K38/28;A61K38/47;A61P3/10;A61P5/50 主分类号 A61K38/28
代理机构 代理人
主权项
地址
您可能感兴趣的专利