发明名称 Ror gamma modulators
摘要 Provided is the use of polyhydroxylated cholane derivatives of formula II or IIa, wherein the variables are as defined in the specification, for the manufacture of a medicament for the treatment of type II diabetes and diseases, disorders and conditions which are related to type II diabetes, such as hyperglycemia. An example of the derivatives is 1beta,3alpha,7alpha,12alpha-Tetrahydroxy-5beta-cholan-24-oate.
申请公布号 NZ620485(A) 申请公布日期 2016.04.29
申请号 NZ20120620485 申请日期 2012.09.18
申请人 ETH ZÜRICH 发明人 WOLFRUM CHRISTIAN;CARREIRA ERICK;MEISSBURGER BETTINA
分类号 A61K31/575;A61K31/58;A61P3/10;C07J9/00;C07J71/00 主分类号 A61K31/575
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