发明名称 DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND
摘要 Provided is a compound useful as an inhibitor against the kinase activity of EML4-ALK fusion protein. As a result of intensive and extensive studies on compounds having inhibitory activity against the kinase activity of EMLA-ALK fusion protein, the present inventors found that the diamino heterocyclic carboxamide compounds of the present invention had inhibitory activity against the kinase activity of EML4-ALK fusion protein. By this finding, the present invention was completed. The compounds of the present invention can be used as a pharmaceutical composition for preventing and/or treating cancer, such as lung cancer, non-small cell lung cancer, and small cell lung cancer.
申请公布号 SI2428508(T1) 申请公布日期 2016.04.29
申请号 SI20100031107T 申请日期 2010.05.06
申请人 ASTELLAS PHARMA INC.;KOTOBUKI PHARMACEUTICAL CO., LTD. 发明人 SHIMADA ITSURO;KUROSAWA KAZUO;MATSUYA TAKAHIRO;IIKUBO KAZUHIKO;KONDOH YUTAKA;KAMIKAWA AKIO;TOMIYAMA HIROSHI;IWAI YOSHINORI
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