发明名称 METHOD FOR MAKING ANTIBODY FC-HETERODIMERIC MOLECULES USING ELECTROSTATIC STEERING EFFECTS
摘要 The invention relates to methods of making Fc-heterodimeric proteins or polypeptides. The invention also relates to the Fc-heterodimeric proteins or polypeptides themselves, including the individual polypeptide components that comprise the heterodimer. Nucleic acids encoding such polypeptides, expression vectors, and host cells. Moreover, the invention relates to pharmaceutical compositions comprising one of more Fc-heterodimeric proteins or polypeptides.
申请公布号 SI2235064(T1) 申请公布日期 2016.04.29
申请号 SI20090031342T 申请日期 2009.01.06
申请人 AMGEN INC. 发明人 KANNAN GUNASEKARAN;WITTEKIND MICHAEL;YAN WEI;PENTONY MARTIN
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