发明名称 CYTOTOXIC BENZODIAZEPINE DERIVATIVES
摘要 The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VII). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention.
申请公布号 SI2675479(T1) 申请公布日期 2016.04.29
申请号 SI20120030460T 申请日期 2012.02.15
申请人 IMMUNOGEN, INC. 发明人 LI WEI;MILLER MICHAEL;FISHKIN NATHAN;CHARI RAVI V. J.
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