COMPOSTI DI 3,4-DIIDROPIRAZINO[2,3-B]PIRAZIN-2(1 H)-ONE COME INIBITORI DI CHINASI MTOR PER INDICAZIONI ONCOLOGICHE E MALATTIE ASSOCIATE AL PERCORSO MTOR/P13K/AKT

摘要

Provided herein are Heteroaryl Compounds having the following structure:
wherein R 1 -R 3 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and a Heteroaryl Compound provided herein for use in a method of treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions.