摘要 |
The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors:
in which R 1 , R 2 , R 3 , R 4 , and R 5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of proliferative diseases, as well as to intermediate compounds useful in the preparation of said compounds. |
申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
KOPPITZ, MARCUS M;SCHULZE, VOLKER V;KOSEMUND, DIRK D;SCHIROK, HARTMUT H;BADER, BENJAMIN B;LIENAU, PHILIPP P;MARQUARDT, TOBIAS T;WEGSCHEID-GERLACH, CHRISTOF C-;SIEMEISTER, GERHARD G;PRECHTL, STEFAN S;WENGNER, ANTJE, MARGRET AM;BOEMER, ULF U |