发明名称 Human antibodies to human tnf-like ligand 1a (tl1a)
摘要 Disclosed is the use of an antibody or antigen-binding fragment thereof in the manufacture of a medicament for treating a disease or disorder which is prevented, ameliorated, improved or inhibited by removal, inhibition or reduction of human TNF-like ligand 1A (hTL1A) activity, wherein the antibody comprises a heavy chain complementarity determining region 1 (HCDR1), HCDR2, and HCDR3 sequence combination of SEQ ID NO: 20/22/24; and/or a light chain complementarity determining region 1 (LCDR1), LCDR2, and LCDR3 sequence combination of SEQ ID NO: 28/30/32, wherein the sequences are as defined in the complete specification.
申请公布号 NZ706986(A) 申请公布日期 2016.04.29
申请号 NZ20110706986 申请日期 2011.11.08
申请人 REGENERON PHARMACEUTICALS INC. 发明人 CLASSON BRENDAN J.;SKOKOS DIMITRIS
分类号 C07K16/28 主分类号 C07K16/28
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