发明名称 INDOLE CARBOXAMIDES COMPOUNDS USEFUL AS KINASE INHOBITORS
摘要 Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
申请公布号 WO2016065226(A1) 申请公布日期 2016.04.28
申请号 WO2015US57055 申请日期 2015.10.23
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 AHMAD, SALEEM;TINO, JOSEPH A.;MACOR, JOHN E.;TEBBEN, ANDREW J.;GONG, HUA;LIU, QINGJIE;BATT, DOUGLAS G.;NGU, KHEHYONG;WATTERSON, SCOTT HUNTER;GUO, WEIWEI;BEAUDOIN BERTRAND, MYRA
分类号 C07D403/12;A61K31/4045;A61P29/00;A61P37/00;C07D209/18;C07D401/04;C07D401/06;C07D401/12;C07D403/04;C07D403/10;C07D413/04;C07D417/04;C07D471/04;C07D487/04;C07D487/10 主分类号 C07D403/12
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