METHODS AND FORMULATION FOR IMPROVING ORAL AVAILABILITY OF CPT-11 WHILE REDUCING CPT-11 INDUCED GASTRONINTESTINAL TOXICITY IN CANCER THERAPY

摘要

Disclosed herein are methods and formulation for enhancing oral availability of CPT-11 during cancer therapy while at the same time, reducing its gastrointestinal (GI) toxicity, thus the methods and formulations as disclosed herein may augment the efficacy of cancer therapy.