DNA VACCINE COMPOSITION FOR PREVENTING AND TREATING HERPES ZOSTER, AND METHOD FOR ACTIVATING T CELLS FOR VZV ANTIGEN BY USING SAME
摘要
The present invention provides a DNA vaccine composition for preventing and treating herpes zoster, containing: at least one type of plasmid containing the insertion site of a varicella-zoster virus (VZV)-derived gene encoding a VZV protein; and other pharmaceutically acceptable ingredients. The plasmid contains a plurality of plasmids containing the insertion site of heterologous genes which are different from each other. The plasmid contains: a first plasmid containing the insertion site of a first gene encoding IE-62 protein (SEQ ID NO: 1); a second plasmid containing the insertion site of a second gene encoding IE-63 protein (SEQ ID NO: 2); and a third plasmid containing the insertion site of a third gene encoding gE protein (SEQ ID NO: 3).
申请公布号
WO2016064063(A1)
申请公布日期
2016.04.28
申请号
WO2015KR06043
申请日期
2015.06.16
申请人
GENEONE LIFE SCIENCE CO., LTD.
发明人
PARK, YOUNG KUN;CHO, BYUNG MUN;JEONG, MOON SUP;LEE, HYO JIN;CHO, YOUNG RAN;OH, JOO YEON