Triazole-substituted arylamide derivatives and their use as P2X3 and /or P2X2/3 purinergic receptor antagonists

摘要

Abstract Compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein, R 1 is optionally substituted triazolyl, and R2 , R3 , R4 , R', R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X 3 and/or a P2X 2/3 receptor antagonists and methods of making the compounds. H:/tzm/Interwoven/NRPortbl/DCC/TZM/5878555_1.DOC - 9/12/13