发明名称 |
Preparation process of (6R)-tetrahydrobiopterin hydrochloride |
摘要 |
A preparation process of (6R)-tetrahydrobiopterin hydrochloride is provided, which comprises hydrogenating L-biopterin in the presence of a catalyst of Pt group metal in the basic substrate containing solvent, potassium hydroxide and potassium dihydrogen phosphate to obtain (6R)-tetrahydrobiopterin hydrochloride, wherein the pH value of the basic substrate is controlled by potassium hydroxide and potassium dihydrogen phosphate in the range of about 10 to about 13. |
申请公布号 |
AU2010362498(B2) |
申请公布日期 |
2016.04.28 |
申请号 |
AU20100362498 |
申请日期 |
2010.11.15 |
申请人 |
INNOPHARMAX, INC. |
发明人 |
WANG, ZHEN;ZHAO, DONGBING;WANG, WEIDA;LAN, JINGBO;YOU, JINGSONG |
分类号 |
C07D475/04 |
主分类号 |
C07D475/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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