发明名称 |
CELL DIFFERENTIATION DEVICES AND METHODS |
摘要 |
Methods, devices, and kits are provided for identifying, selecting, and/or manipulating live cells in a sample comprising a suspected mixed population of cells by subjecting the sample located in a first position to a linear gradient of a cellular stimulus to induce a change in a live cell sufficient to induce movement of the cell from a first position to a second position, wherein a dead cell, if present in the sample, is not induced to move to the second position in the presence of the cellular stimulus; and identifying or selecting the live cell in the second position. |
申请公布号 |
US2016115519(A1) |
申请公布日期 |
2016.04.28 |
申请号 |
US201514925558 |
申请日期 |
2015.10.28 |
申请人 |
GEORGIA TECH RESEARCH CORPORATION |
发明人 |
HESKETH Peter J.;Britton Douglas;Daley Wayne D.;Mahdavifar Alireza;Xu Jie |
分类号 |
C12Q1/10;B01L3/00 |
主分类号 |
C12Q1/10 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method for manipulating live cells in a sample comprising a suspected mixed population of cells, comprising:
(a) subjecting the sample located in a first position to a linear gradient of a cellular stimulus to induce a change in a live cell sufficient to induce movement of the cell from a first position to a second position, wherein a dead cell, if present in the sample, is not induced to move to the second position in the presence of the cellular stimulus; and (b) identifying or selecting the live cell in the second position. |
地址 |
Atlanta GA US |