发明名称 |
NEW THIENOPYRIMIDINE DERIVATIVES AS NIK INHIBITORS |
摘要 |
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-κB-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders. |
申请公布号 |
WO2016062789(A1) |
申请公布日期 |
2016.04.28 |
申请号 |
WO2015EP74430 |
申请日期 |
2015.10.22 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
HYND, GEORGE;TISSELLI, PATRIZIA;MACLEOD, CALUM;MANN, SAMUEL, EDWARD;MONTANA, JOHN, GARY;PRICE, STEPHEN, COLIN |
分类号 |
C07D519/00;A61K45/06;A61P35/00 |
主分类号 |
C07D519/00 |
代理机构 |
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