Systems and Methods for Neurostimulation Electrode Configurations Based on Neural Localization

摘要

Methods and systems for obtaining and analyzing electromyography responses of electrodes of an implanted neurostimulation lead for use neurostimulation programming are provided herein. System setups for neural localization and/or programming include a clinician programmer coupleable with a temporary or permanent lead implantable in a patient and at least one pair of EMG sensing electrodes minimally invasively positioned on a skin surface or within the patient. The clinician programmer is configured to determine a plurality of recommended electrode configurations based on thresholds and EMG responses of the plurality of electrodes and rank the electrode configuration according to pre-determined criteria. The clinician programmer further includes graphical user interface on which the plurality of recommended electrode configurations are displayed for modification and/or selection by a clinician in programming an IPG or EPG coupled with the lead to apply a neurostimulation treatment according to the selected electrode configuration.

主权项

1. A method of programming a neurostimulation device coupled with a plurality of electrodes of a neurostimulation lead implanted near a target nerve for treatment of overactive bladder and/or fecal incontinence, the method comprising:
obtaining a stimulation threshold for each of the plurality of electrodes with a clinician programming device via input ports connecting the plurality of electrodes to the clinician computing device, wherein the stimulation threshold is based, at least in part, on an EMG recording of at least one neuromuscular response during stimulation of a given electrode of the plurality of electrodes; determining a plurality of electrode configurations with the clinician programming device that are suitable for delivery of neurostimulation; identifying one or more neurostimulation programs corresponding to an electrode configuration selected from the plurality of electrode configurations, wherein identifying the one or more neurostimulation programs is based, at least in part, on the stimulation thresholds obtained by the clinician programming device; applying the one or more identified programs and recording an EMG response with the clinician programming device; and determining a first neurostimulation program for treatment of overactive bladder and/or fecal incontinence based on the one or more programs.