MicroRNA inhibitors for treatment of vascular disorders and for vascular re-modelling

摘要

The present invention is based on the finding that micro RNA from the micro RNA gene cluster located on the human chromosomal at locus 14q32 play an important role in vascular development and re-modelling. Modulators of any of the 14q32 micro RNA may be exploited as a means to modulate vascular re-modelling processes and/or in the treatment and/or prevention of vascular disorders or disease.