| 摘要 |
PROBLEM TO BE SOLVED: To provide a production method of an antiviral drug obtained from microalgae in which the remained amount of a lipid is little, and an antiviral activity and immune activity are enhanced to new and seasonal human influenza virus, coronavirus, and norovirus; and to provide an antiviral drug obtained by the method.SOLUTION: The invention provides a production method of an antiviral drug having an antiviral activity enhanced to the above viruses, the method comprising performing two or more degreasing operations of mixing Coccomyxa or Chlorella of microalgae, benzene:methanol (2:1), or a volatile solvent consisting of ethanol, acetone, and hexane, and centrifuging in combination with one or more of ultrasonic vibration, hyperbaric pressure homogenization, and blade-agitation; adding given amount of water after the degreasing step, and heating over a given time to extract with hot water; and concentrating and drying a solution layer subjected to solid liquid separation by centrifugation of the hot water extract.SELECTED DRAWING: None |
