Systems and Methods for Sample Preparation, Processing and Analysis

摘要

The present disclosure provides systems and methods for sample preparation, processing and analysis. Also provided in the present disclosure is a fully-integrated electrophoresis cartridge which has a small footprint and configured to removably engage with the system.

主权项

1. An electrophoresis cartridge adapted to releasably engage with a cartridge interface of a system, wherein the electrophoresis cartridge comprises:
an electrophoresis assembly including:
(1) an anode sub-assembly comprising an anode,(2) a cathode sub-assembly comprising a cathode; and(3) at least one electrophoresis capillary having a first end and a second end, wherein said cathode and said anode are configured to provide a voltage gradient across said first end and said second end of said at least one electrophoresis capillary, wherein said electrophoresis cartridge is engageable with said cartridge interface to permit automatically establishing at least one of:
(i) an optical communication between said system and a portion of said at least one electrophoresis capillary;(ii) an electrical communication between said system and said anode and said cathode;(iii) a fluidic communication between said system and said at least one electrophoresis capillary;(iv) a thermal communication between said system and said electrophoresis cartridge or said at least one electrophoresis capillary;(v) an electromagnetic communication between said system and said electrophoresis cartridge; and(vi) a magnetic communication between said system and said electrophoresis cartridge.