发明名称 |
ANTI-MUTANT PROTEIN S ANTIBODY, DIAGNOSIS COMPOSITION CONTAINING ANTIBODY THEREOF, DETECTION METHOD FOR MUTANT HUMAN PROTEIN S, AND KIT CONTAINING ANTIBODY THEREOF |
摘要 |
PROBLEM TO BE SOLVED: To provide an antibody which enable the accurate and convenient detection of a mutant protein S having K196E mutation, or a fragment thereof, to provide an immunological diagnosis composition containing the antibody or a fragment thereof, to provide a method for detecting mutant human protein S, and to provide a kit containing the antibody or a fragment thereof.SOLUTION: The invention provides an antibody or a fragment thereof which binds to CKNGFVMLSNE (sequence ID NO. 2) with significantly higher affinity than to CKNGFVMLSNK (sequence ID NO. 3).SELECTED DRAWING: Figure 5 |
申请公布号 |
JP2016065008(A) |
申请公布日期 |
2016.04.28 |
申请号 |
JP20140194080 |
申请日期 |
2014.09.24 |
申请人 |
EIKEN CHEMICAL CO LTD;NATIONAL CEREBRAL & CARDIOVASCULAR CENTER;KANAZAWA UNIV |
发明人 |
MIYATA TOSHIYUKI;AKIYAMA MASASHI;MARUYAMA KEIKO;MORISHITA ERIKO |
分类号 |
C07K16/18;G01N33/53;G01N33/543 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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