发明名称 ANTI-MUTANT PROTEIN S ANTIBODY, DIAGNOSIS COMPOSITION CONTAINING ANTIBODY THEREOF, DETECTION METHOD FOR MUTANT HUMAN PROTEIN S, AND KIT CONTAINING ANTIBODY THEREOF
摘要 PROBLEM TO BE SOLVED: To provide an antibody which enable the accurate and convenient detection of a mutant protein S having K196E mutation, or a fragment thereof, to provide an immunological diagnosis composition containing the antibody or a fragment thereof, to provide a method for detecting mutant human protein S, and to provide a kit containing the antibody or a fragment thereof.SOLUTION: The invention provides an antibody or a fragment thereof which binds to CKNGFVMLSNE (sequence ID NO. 2) with significantly higher affinity than to CKNGFVMLSNK (sequence ID NO. 3).SELECTED DRAWING: Figure 5
申请公布号 JP2016065008(A) 申请公布日期 2016.04.28
申请号 JP20140194080 申请日期 2014.09.24
申请人 EIKEN CHEMICAL CO LTD;NATIONAL CEREBRAL & CARDIOVASCULAR CENTER;KANAZAWA UNIV 发明人 MIYATA TOSHIYUKI;AKIYAMA MASASHI;MARUYAMA KEIKO;MORISHITA ERIKO
分类号 C07K16/18;G01N33/53;G01N33/543 主分类号 C07K16/18
代理机构 代理人
主权项
地址