| 摘要 |
The invention relates to a method for the preparation of radiochemical compounds using a device having at least a reaction module, a dosing module, and a storage module, wherein the reaction module has at least one reaction vessel having a closable opening through which substances needed for the preparation of a predetermined radiochemical compound can be introduced into the reaction vessel of the reaction module and through which the prepared radiochemical compound can be removed from the reaction vessel of the reaction module; the dosing module has at least one pipetting head which can be moved relative to the storage module and the reaction module and in x, y, and z directions and also has at least one dosing unit; and at least one reservoir for one of the substances needed for the preparation of the respective radiochemical compound is formed in the storage module. Substances needed for the preparation of the respective radiochemical compound are introduced into the reaction vessel of the reaction module by means of dosing units, wherein the dosing units can be moved via a pipetting head in x, y directions or in x, y, and z directions. |
| 主权项 |
1. A method for the preparation of radiochemical compounds comprising:
introducing substances needed for the preparation of a respective radiochemical compound by means of dosing units into a reaction vessel of a reaction module of a device comprising at least one reaction module, a dosing module, and a storage module, wherein the reaction module has at least one reaction vessel having a closable opening through which substances needed for the preparation of a predetermined radiochemical compound can be introduced into the reaction vessel of the reaction module and through which the prepared radiochemical compound can be removed from the reaction vessel of the reaction module, the dosing module having at least one pipetting head which can be moved relative to the storage module and the reaction module and in x, y, and z directions and also having one or more dosing units, wherein at least one dosing unit is a triple lumen dosing unit having a first channel for taking up, transporting, and releasing a substance needed for the synthesis of the radio-chemical compound, a second channel for supplying a gas into a reaction vessel and a third channel for draining off gaseous reaction products from the reaction vessel, and at least one reservoir for one of the substances needed for the preparation of the respective radiochemical compound is formed in the storage module, wherein purification means required for the separation of the prepared radiochemical compound from the reaction mixture are integrated into the storage module, and wherein the reaction module, the dosing module, and the storage module are arranged in a hot cell; wherein the dosing units are movable via a pipetting head in x, y directions or in x, y, and z directions. |
